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Synthesis of taurine–fluorescein conjugate and evaluation of its retina-targeted efficiency in vitro
In this work, retinal penetration of fluorescein was achieved in vitro by covalent attachment of taurine to fluorescein, yielding the F–Tau conjugate. Nuclear magnetic resonance (NMR) and high resolution mass spectrometry (HRMS) were used to confirm the successful synthesis of F–Tau. The cellular up...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629109/ https://www.ncbi.nlm.nih.gov/pubmed/26579416 http://dx.doi.org/10.1016/j.apsb.2014.10.006 |