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IL-10-producing CD4(+) T cells negatively regulate fucosylation of epithelial cells in the gut

Fucosylated glycans on the surface of epithelial cells (ECs) regulate intestinal homeostasis by serving as attachment receptors and a nutrient source for some species of bacteria. We show here that epithelial fucosylation in the ileum is negatively regulated by IL-10-producing CD4(+) T cells. The nu...

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Detalles Bibliográficos
Autores principales: Goto, Yoshiyuki, Lamichhane, Aayam, Kamioka, Mariko, Sato, Shintaro, Honda, Kenya, Kunisawa, Jun, Kiyono, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629126/
https://www.ncbi.nlm.nih.gov/pubmed/26522513
http://dx.doi.org/10.1038/srep15918