Deacetylation-mediated interaction of SIRT1-HMGB1 improves survival in a mouse model of endotoxemia

Inflammatory signal-mediated release of high-mobility group box 1 (HMGB1) is a damage-associated molecular pattern or alarmin. The inflammatory functions of HMGB1 have been extensively investigated; however, less is known about the mechanisms controlling HMGB1 release. We show that SIRT1, the human...

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Detalles Bibliográficos
Autores principales: Hwang, Jung Seok, Choi, Hyuk Soo, Ham, Sun Ah, Yoo, Taesik, Lee, Won Jin, Paek, Kyung Shin, Seo, Han Geuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629154/
https://www.ncbi.nlm.nih.gov/pubmed/26522327
http://dx.doi.org/10.1038/srep15971

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629154/
https://www.ncbi.nlm.nih.gov/pubmed/26522327
http://dx.doi.org/10.1038/srep15971

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