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Fluoxetine regulates mTOR signalling in a region-dependent manner in depression-like mice

Previous studies have demonstrated that the mammalian target of rapamycin (mTOR) signaling pathway has an important role in ketamine-induced, rapid antidepressant effects despite the acute administration of fluoxetine not affecting mTOR phosphorylation in the brain. However, the effects of long-term...

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Detalles Bibliográficos
Autores principales: Liu, Xiao-Long, Luo, Liu, Mu, Rong-Hao, Liu, Bin-Bin, Geng, Di, Liu, Qing, Yi, Li-Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629199/
https://www.ncbi.nlm.nih.gov/pubmed/26522512
http://dx.doi.org/10.1038/srep16024