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In vitro and in vivo evaluation of cubosomes containing 5-fluorouracil for liver targeting

The objective of this study was to prepare cubosomal nanoparticles containing a hydrophilic anticancer drug 5-fluorouracil (5-FU) for liver targeting. Cubosomal dispersions were prepared by disrupting a cubic gel phase of monoolein and water in the presence of Poloxamer 407 as a stabilizer. Cubosome...

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Detalles Bibliográficos
Autores principales: Nasr, Mohamed, Ghorab, Mohamed K., Abdelazem, Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629209/
https://www.ncbi.nlm.nih.gov/pubmed/26579429
http://dx.doi.org/10.1016/j.apsb.2014.12.001