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In vitro and in vivo evaluation of cubosomes containing 5-fluorouracil for liver targeting
The objective of this study was to prepare cubosomal nanoparticles containing a hydrophilic anticancer drug 5-fluorouracil (5-FU) for liver targeting. Cubosomal dispersions were prepared by disrupting a cubic gel phase of monoolein and water in the presence of Poloxamer 407 as a stabilizer. Cubosome...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629209/ https://www.ncbi.nlm.nih.gov/pubmed/26579429 http://dx.doi.org/10.1016/j.apsb.2014.12.001 |