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Design, synthesis and evaluation of genistein-polyamine conjugates as multi-functional anti-Alzheimer agents
A series of genistein-polyamine conjugates (4a–4h) were designed, synthesized and evaluated as multi-functional anti-Alzheimer agents. The results showed that these compounds had significant cholinesterases (ChEs) inhibitory activity. Compound 4b exhibited the strongest inhibition to acetylcholinest...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629212/ https://www.ncbi.nlm.nih.gov/pubmed/26579427 http://dx.doi.org/10.1016/j.apsb.2014.12.008 |