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Nanocarrier-mediated co-delivery of chemotherapeutic drugs and gene agents for cancer treatment

The efficacy of chemotherapeutic drug in cancer treatment is often hampered by drug resistance of tumor cells, which is usually caused by abnormal gene expression. RNA interference mediated by siRNA and miRNA can selectively knock down the carcinogenic genes by targeting specific mRNAs. Therefore, c...

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Detalles Bibliográficos
Autores principales: Kang, Lin, Gao, Zhonggao, Huang, Wei, Jin, Mingji, Wang, Qiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629232/
https://www.ncbi.nlm.nih.gov/pubmed/26579443
http://dx.doi.org/10.1016/j.apsb.2015.03.001