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WU-CRISPR: characteristics of functional guide RNAs for the CRISPR/Cas9 system
The CRISPR/Cas9 system has been rapidly adopted for genome editing. However, one major issue with this system is the lack of robust bioinformatics tools for design of single guide RNA (sgRNA), which determines the efficacy and specificity of genome editing. To address this pressing need, we analyze...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629399/ https://www.ncbi.nlm.nih.gov/pubmed/26521937 http://dx.doi.org/10.1186/s13059-015-0784-0 |