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A Her2-let-7-β2-AR circuit affects prognosis in patients with Her2-positive breast cancer

BACKGROUND: Our previous studies show that β2-adrenergic receptor (β2-AR) is highly expressed in most Her2-overexpressing breast cancers. However, the mechanisms underlying upregulation of the β2-AR expression in Her2-overexpressing breast cancer cells are not fully understood. The clinical signific...

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Detalles Bibliográficos
Autores principales: Liu, Dan, Deng, Que, Sun, Limin, Wang, Tao, Yang, Zhengyan, Chen, Hongyu, Guo, Liang, Liu, Yanjun, Ma, Yuanfang, Guo, Ning, Shi, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629406/
https://www.ncbi.nlm.nih.gov/pubmed/26526356
http://dx.doi.org/10.1186/s12885-015-1869-6