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Single molecule FRET observation of kinesin-1’s head-tail interaction on microtubule

Kinesin-1 (conventional kinesin) is a molecular motor that transports various cargo such as endoplasmic reticulum and mitochondria in cells. Its two head domains walk along microtubule by hydrolyzing ATP, while the tail domains at the end of the long stalk bind to the cargo. When a kinesin is not ca...

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Detalles Bibliográficos
Autores principales: Aoki, Takahiro, Tomishige, Michio, Ariga, Takayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society of Japan (BSJ) 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629677/
https://www.ncbi.nlm.nih.gov/pubmed/27493553
http://dx.doi.org/10.2142/biophysics.9.149