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Cigarette smoke–induced induction of antioxidant enzyme activities in airway leukocytes is absent in active smokers with COPD

BACKGROUND: Oxidative injury to the airway has been proposed as an important underlying mechanism in the pathogenesis of chronic obstructive pulmonary disease (COPD). As the extent of oxidant-mediated damage is dependent on the endogenous antioxidant defences within the airways, we examined whether...

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Detalles Bibliográficos
Autores principales: Dove, Rosamund E., Leong-Smith, Pheneatia, Roos-Engstrand, Ester, Pourazar, Jamshid, Shah, Mittal, Behndig, Annelie F., Mudway, Ian S., Blomberg, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Co-Action Publishing 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629722/
https://www.ncbi.nlm.nih.gov/pubmed/26557249
http://dx.doi.org/10.3402/ecrj.v2.27837