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The Extracellular Domains of IgG1 and T Cell-Derived IL-4/IL-13 Are Critical for the Polyclonal Memory IgE Response In Vivo

IgE-mediated activation of mast cells and basophils contributes to protective immunity against helminths but also causes allergic responses. The development and persistence of IgE responses are poorly understood, which is in part due to the low number of IgE-producing cells. Here, we used next gener...

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Detalles Bibliográficos
Autores principales: Turqueti-Neves, Adriana, Otte, Manuel, Schwartz, Christian, Schmitt, Michaela Erika Renate, Lindner, Cornelia, Pabst, Oliver, Yu, Philipp, Voehringer, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629909/
https://www.ncbi.nlm.nih.gov/pubmed/26523376
http://dx.doi.org/10.1371/journal.pbio.1002290