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Endogenous antigen processing drives the primary CD4(+) T cell response to influenza

By convention, CD4(+) T lymphocytes recognize foreign and self peptides derived from internalized antigens in combination with MHC class II molecules. Alternative pathways of epitope production have been identified but their contributions to host defense have not been established. We show here in a...

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Detalles Bibliográficos
Autores principales: Miller, Michael A., Ganesan, Asha Purnima V., Luckashenak, Nancy, Mendonca, Mark, Eisenlohr, Laurence C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629989/
https://www.ncbi.nlm.nih.gov/pubmed/26413780
http://dx.doi.org/10.1038/nm.3958