Sazetidine-A Activates and Desensitizes Native α7 Nicotinic Acetylcholine Receptors

The aim of this study was to investigate the ability of sazetidine-A, a novel partial agonist at α4β2 nicotinic acetylcholine receptors (nAChRs), to affect the function of native α7 nAChRs in SH-SY5Y cells and primary cortical cultures. The α7-selective positive allosteric modulator PNU-120596 was u...

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Detalles Bibliográficos
Autores principales: Brown, Jack L., Wonnacott, Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2014
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630245/
https://www.ncbi.nlm.nih.gov/pubmed/24728867
http://dx.doi.org/10.1007/s11064-014-1302-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630245/
https://www.ncbi.nlm.nih.gov/pubmed/24728867
http://dx.doi.org/10.1007/s11064-014-1302-6

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