Cargando…

Changes in Membrane Cholesterol Differentially Influence Preferential and Non-preferential Signaling of the M1 and M3 Muscarinic Acetylcholine Receptors

We have found earlier that changes in membrane cholesterol content have distinct impact on signaling via the M1, M2, or M3 receptors expressed in CHO cells (CHO-M1 through CHO-M3). Now we investigated whether gradual changes in membrane cholesterol exerts differential effects on coupling of the M1 a...

Descripción completa

Detalles Bibliográficos
Autores principales: Michal, Pavel, El-Fakahany, Esam E., Doležal, Vladimír
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630253/
https://www.ncbi.nlm.nih.gov/pubmed/24821386
http://dx.doi.org/10.1007/s11064-014-1325-z