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Brain-specific transcriptional regulator T-brain-1 controls brain wiring and neuronal activity in autism spectrum disorders

T-brain-1 (TBR1) is a brain-specific T-box transcription factor. In 1995, Tbr1 was first identified from a subtractive hybridization that compared mouse embryonic and adult telencephalons. Previous studies of Tbr1(−∕−) mice have indicated critical roles for TBR1 in the development of the cerebral co...

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Detalles Bibliográficos
Autores principales: Huang, Tzyy-Nan, Hsueh, Yi-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630302/
https://www.ncbi.nlm.nih.gov/pubmed/26578866
http://dx.doi.org/10.3389/fnins.2015.00406