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ROS-Mediated NLRP3 Inflammasome Activity Is Essential for Burn-Induced Acute Lung Injury

The NLRP3 inflammasome is necessary for initiating acute sterile inflammation. However, its role in the pathogenesis of burn-induced acute lung injury (ALI) is unknown. This study aimed to determine the role of the NLRP3 inflammasome and the signaling pathways involved in burn-induced ALI. We observ...

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Detalles Bibliográficos
Autores principales: Han, Shichao, Cai, Weixia, Yang, Xuekang, Jia, Yanhui, Zheng, Zhao, Wang, Hongtao, Li, Jun, Li, Yan, Gao, Jianxin, Fan, Lei, Hu, Dahai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630408/
https://www.ncbi.nlm.nih.gov/pubmed/26576075
http://dx.doi.org/10.1155/2015/720457