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Interleukin-17 promotes angiogenesis by stimulating VEGF production of cancer cells via the STAT3/GIV signaling pathway in non-small-cell lung cancer

The presence of IL-17-positive cells is observed in a variety of inflammatory associated cancers and IL-17 has been found to be involved in angiogenesis. However, it remains unclear how IL-17 might contribute to tumor angiogenesis. In our study, IL-17 enhanced the formation of vessel-like tubes in H...

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Detalles Bibliográficos
Autores principales: Pan, Bo, Shen, Jing, Cao, Jingyan, Zhou, Yongxu, Shang, Lihua, Jin, Shi, Cao, Shoubo, Che, Dehai, Liu, Fang, Yu, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630609/
https://www.ncbi.nlm.nih.gov/pubmed/26524953
http://dx.doi.org/10.1038/srep16053