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The Plasmodium palmitoyl-S-acyl-transferase DHHC2 is essential for ookinete morphogenesis and malaria transmission

The post-translational addition of C-16 long chain fatty acids to protein cysteine residues is catalysed by palmitoyl-S-acyl-transferases (PAT) and affects the affinity of a modified protein for membranes and therefore its subcellular localisation. In apicomplexan parasites this reversible protein m...

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Detalles Bibliográficos
Autores principales: Santos, Jorge M., Kehrer, Jessica, Franke-Fayard, Blandine, Frischknecht, Friedrich, Janse, Chris J., Mair, Gunnar R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630622/
https://www.ncbi.nlm.nih.gov/pubmed/26526684
http://dx.doi.org/10.1038/srep16034