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NFAT isoforms play distinct roles in TNFα-induced retinal leukostasis

The objective of this study was to determine the role of individual NFAT isoforms in TNFα-induced retinal leukostasis. To this end, human retinal microvascular endothelial cells (HRMEC) transfected with siRNA targeting individual NFAT isoforms were treated with TNFα, and qRT-PCR was used to examine...

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Detalles Bibliográficos
Autores principales: Bretz, Colin A., Savage, Sara R., Capozzi, Megan E., Suarez, Sandra, Penn, John S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630625/
https://www.ncbi.nlm.nih.gov/pubmed/26527057
http://dx.doi.org/10.1038/srep14963