Mouse adaptation of influenza B virus increases replication in the upper respiratory tract and results in droplet transmissibility in ferrets

To investigate the molecular changes that allow influenza B viruses to adapt to new mammalian hosts, influenza B/Florida/04/2006 was serially passaged in BALB/c mice until highly virulent. The viral factors underlying this transition were then investigated in mice and ferrets. Five viruses, includin...

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Detalles Bibliográficos
Autores principales: Kim, Eun-Ha, Park, Su-Jin, Kwon, Hyeok-Il, Kim, Se Mi, Kim, Young-il, Song, Min-Suk, Choi, Eun-Ji, Pascua, Philippe Noriel Q., Choi, Young-Ki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630645/
https://www.ncbi.nlm.nih.gov/pubmed/26526113
http://dx.doi.org/10.1038/srep15940

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630645/
https://www.ncbi.nlm.nih.gov/pubmed/26526113
http://dx.doi.org/10.1038/srep15940

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