Regulation of MUTYH, a DNA Repair Enzyme, in Renal Proximal Tubular Epithelial Cells

MUTYH is a DNA repair enzyme that initiates a base excision repair (BER) by recognizing and removing 8-Oxoguanine (8-oxoG) and its paired adenine. We demonstrated that both TGF-β1 and H(2)O(2) treatment led to an increased 8-oxoG in cultured human proximal tubule epithelial (HK-2) cells, while the f...

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Detalles Bibliográficos
Autores principales: Lu, Jianping, Li, Xinxiu, Zhang, Mingcao, Chen, Zhaohong, Wang, Yaping, Zeng, Caihong, Liu, Zhihong, Chen, Huimei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630661/
https://www.ncbi.nlm.nih.gov/pubmed/26576226
http://dx.doi.org/10.1155/2015/682861

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630661/
https://www.ncbi.nlm.nih.gov/pubmed/26576226
http://dx.doi.org/10.1155/2015/682861

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