Mechanisms of Neuronal Protection against Excitotoxicity, Endoplasmic Reticulum Stress, and Mitochondrial Dysfunction in Stroke and Neurodegenerative Diseases

In stroke and neurodegenerative disease, neuronal excitotoxicity, caused by increased extracellular glutamate levels, is known to result in calcium overload and mitochondrial dysfunction. Mitochondrial deficits may involve a deficiency in energy supply as well as generation of high levels of oxidant...

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Detalles Bibliográficos
Autores principales: Prentice, Howard, Modi, Jigar Pravinchandra, Wu, Jang-Yen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630664/
https://www.ncbi.nlm.nih.gov/pubmed/26576229
http://dx.doi.org/10.1155/2015/964518

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630664/
https://www.ncbi.nlm.nih.gov/pubmed/26576229
http://dx.doi.org/10.1155/2015/964518

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