Adrenergic stimulation sensitizes TRPV1 through upregulation of cystathionine β-synthetase in a rat model of visceral hypersensitivity

The pathogenesis of pain in irritable bowel syndrome (IBS) is poorly understood and treatment remains difficult. The present study was designed to investigate roles of adrenergic signaling and the endogenous hydrogen sulfide producing enzyme cystathionine β-synthetase (CBS) in a previously validated...

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Detalles Bibliográficos
Autores principales: Zhu, Liyan, Zhao, Liting, Qu, Ruobing, Zhu, Hong-Yan, Wang, Yongmeng, Jiang, Xinghong, Xu, Guang-Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630780/
https://www.ncbi.nlm.nih.gov/pubmed/26527188
http://dx.doi.org/10.1038/srep16109

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630780/
https://www.ncbi.nlm.nih.gov/pubmed/26527188
http://dx.doi.org/10.1038/srep16109

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