Cargando…

Adrenergic stimulation sensitizes TRPV1 through upregulation of cystathionine β-synthetase in a rat model of visceral hypersensitivity

The pathogenesis of pain in irritable bowel syndrome (IBS) is poorly understood and treatment remains difficult. The present study was designed to investigate roles of adrenergic signaling and the endogenous hydrogen sulfide producing enzyme cystathionine β-synthetase (CBS) in a previously validated...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhu, Liyan, Zhao, Liting, Qu, Ruobing, Zhu, Hong-Yan, Wang, Yongmeng, Jiang, Xinghong, Xu, Guang-Yin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630780/ https://www.ncbi.nlm.nih.gov/pubmed/26527188 http://dx.doi.org/10.1038/srep16109

Ejemplares similares

Upregulation of Cystathionine β-Synthetase Expression Contributes to Visceral Hyperalgesia Induced by Heterotypic Intermittent Stress in Rats
por: Wang, Yongmeng, et al.
Publicado: (2012)

Upregulation of cystathionine beta-synthetase expression by nuclear factor-kappa B activation contributes to visceral hypersensitivity in adult rats with neonatal maternal deprivation
por: Li, Lin, et al.
Publicado: (2012)

Neonatal Colonic Inflammation Increases Spinal Transmission and Cystathionine β-Synthetase Expression in Spinal Dorsal Horn of Rats with Visceral Hypersensitivity
por: Zhao, Liting, et al.
Publicado: (2017)

Sensitization of P2X3 receptors by cystathionine β-synthetase mediates persistent pain hypersensitivity in a rat model of lumbar disc herniation
por: Wang, Qianliang, et al.
Publicado: (2015)

Neonatal Maternal Deprivation Followed by Adult Stress Enhances Adrenergic Signaling to Advance Visceral Hypersensitivity
por: Du, Wan-Jie, et al.
Publicado: (2018)

Upregulation of cystathionine-β-synthetase expression contributes to inflammatory pain in rat temporomandibular joint
por: Miao, Xiuhua, et al.
Publicado: (2014)

Prenatal maternal stress induces visceral hypersensitivity of adult rat offspring through activation of cystathionine-β-synthase signaling in primary sensory neurons
por: Wang, Hong-Jun, et al.
Publicado: (2018)

The endogenous hydrogen sulfide producing enzyme cystathionine-β synthase contributes to visceral hypersensitivity in a rat model of irritable bowel syndrome
por: Xu, Guang-Yin, et al.
Publicado: (2009)

Adrenergic β(2)-Receptors Mediates Visceral Hypersensitivity Induced by Heterotypic Intermittent Stress in Rats
por: Zhang, Chunhua, et al.
Publicado: (2014)

TRPV1-mediated presynaptic transmission in basolateral amygdala contributes to visceral hypersensitivity in adult rats with neonatal maternal deprivation
por: Xiao, Ying, et al.
Publicado: (2016)

Electroacupuncture Regulates TRPV1 through PAR2/PKC Pathway to Alleviate Visceral Hypersensitivity in FD Rats
por: Han, Yong-li, et al.
Publicado: (2021)

Activating transcription factor (ATF) 6 upregulates cystathionine β synthetase (CBS) expression and hydrogen sulfide (H(2)S) synthesis to ameliorate liver metabolic damage
por: Dong, Bingzi, et al.
Publicado: (2023)

Inhibition of cystathionine β-synthetase suppresses sodium channel activities of dorsal root ganglion neurons of rats with lumbar disc herniation
por: Yan, Jun, et al.
Publicado: (2016)

Upregulation of Netrin-1 in the hippocampus mediates the formation of visceral hypersensitivity induced by maternal separation
por: Wang, Junwen, et al.
Publicado: (2022)

Downregulation of cystathionine β‐synthase and cystathionine γ‐lyase expression stimulates inflammation in kidney ischemia–reperfusion injury
por: Wang, Pengqi, et al.
Publicado: (2014)

Electroacupuncture at ST36 Relieves Visceral Hypersensitivity via the NGF/TrkA/TRPV1 Peripheral Afferent Pathway in a Rodent Model of Post-Inflammation Rectal Hypersensitivity
por: Chen, Yan, et al.
Publicado: (2021)

Decreased miR-199 augments visceral pain in patients with IBS through translational upregulation of TRPV1
por: Zhou, QiQi, et al.
Publicado: (2016)

Neuro-Immune Modulation Effects of Sacral Nerve Stimulation for Visceral Hypersensitivity in Rats
por: Jin, Xue, et al.
Publicado: (2021)

Electroacupuncture at ST36 Relieves Visceral Hypersensitivity via the NGF/TrkA/TRPV1 Peripheral Afferent Pathway in a Rodent Model of Post-Inflammation Rectal Hypersensitivity [Erratum]
Publicado: (2021)

Cystathionine β-Synthase in Physiology and Cancer
por: Zhu, Haoran, et al.
Publicado: (2018)

Unconventional interactions of the TRPV4 ion channel with beta-adrenergic receptor ligands
por: Benítez-Angeles, Miguel, et al.
Publicado: (2022)

Effect and mechanisms of sacral nerve stimulation on visceral hypersensitivity mediated by nerve growth factor
por: Jiang, Liuqin, et al.
Publicado: (2019)

Adrenergic stimulation of adiponectin secretion in visceral mouse adipocytes is blunted in high-fat diet induced obesity
por: Musovic, Saliha, et al.
Publicado: (2019)

Expression of Cystathionine β-synthase and Cystathionine γ-lyase in Human Pregnant Myometrium and Their Roles in the Control of Uterine Contractility
por: You, Xing-Ji, et al.
Publicado: (2011)

TRPV1 antagonist attenuates postoperative hypersensitivity by central and peripheral mechanisms
por: Uchytilova, Eva, et al.
Publicado: (2014)

Inhibition of cystathionine-γ-lyase controls interleukin-12 production by dendritic cells, delayed-type hypersensitivity and transplant rejection
por: Vuillefroy de Silly, Romain, et al.
Publicado: (2012)

Adrenergic receptors inhibit TRPV1 activity in the dorsal root ganglion neurons of rats
por: Matsushita, Yumi, et al.
Publicado: (2018)

3-Mercaptopyruvate Sulfurtransferase, Not Cystathionine β-Synthase Nor Cystathionine γ-Lyase, Mediates Hypoxia-Induced Migration of Vascular Endothelial Cells
por: Tao, Beibei, et al.
Publicado: (2017)

Oncostatin M induces heat hypersensitivity by gp130-dependent sensitization of TRPV1 in sensory neurons
por: Langeslag, Michiel, et al.
Publicado: (2011)

Downregulation of GRK6 in arcuate nucleus promotes chronic visceral hypersensitivity via NF-κB upregulation in adult rats with neonatal maternal deprivation
por: Li, Xin, et al.
Publicado: (2020)

Inhibition of Mast Cell Degranulation Relieves Visceral Hypersensitivity Induced by Pancreatic Carcinoma in Mice
por: Yu, Dawei, et al.
Publicado: (2019)

Effect of the 5-HT(4) receptor and serotonin transporter on visceral hypersensitivity in rats
por: Chi, Yan, et al.
Publicado: (2012)

Cutaneous Hypersensitivity as an Indicator of Visceral Inflammation via C-Nociceptor Axon Bifurcation
por: Fang, Yehong, et al.
Publicado: (2020)

Upregulation of calprotectin in mild IgE-mediated ovalbumin hypersensitivity
por: Zhu, Qingling, et al.
Publicado: (2017)

Sacral nerve stimulation with optimized parameters improves visceral hypersensitivity in rats mediated via the autonomic pathway
por: Jiang, Liuqin, et al.
Publicado: (2019)

Beneficial effect of butyrate‐producing Lachnospiraceae on stress‐induced visceral hypersensitivity in rats
por: Zhang, Jindong, et al.
Publicado: (2018)

Progress on the Mechanism of Visceral Hypersensitivity in Nonerosive Reflux Disease
por: Xu, Cao, et al.
Publicado: (2022)

Activation of β2-Adrenergic Receptors in Microglia Alleviates Neuropathic Hypersensitivity in Mice
por: Damo, Elisa, et al.
Publicado: (2023)

Selectivity of commonly used pharmacological inhibitors for cystathionine β synthase (CBS) and cystathionine γ lyase (CSE)
por: Asimakopoulou, Antonia, et al.
Publicado: (2013)

Colonic Hypersensitivity and Sensitization of Voltage-gated Sodium Channels in Primary Sensory Neurons in Rats with Diabetes
por: Hu, Ji, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_c75jnpudtanpn7p9t7dhmfha6g