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Reprogramming energy metabolism and inducing angiogenesis: co-expression of monocarboxylate transporters with VEGF family members in cervical adenocarcinomas

BACKGROUND: Deregulation of cellular energetic metabolism was recently pointed out as a hallmark of cancer cells. This deregulation involves a metabolic reprogramming that leads to a high production of lactate. Lactate efflux, besides contributing for the glycolytic flux, also acts in the extracellu...

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Detalles Bibliográficos
Autores principales: Pinheiro, Céline, Garcia, Eduardo A., Morais-Santos, Filipa, Moreira, Marise A. R., Almeida, Fábio M., Jubé, Luiz F., Queiroz, Geraldo S., Paula, Élbio C., Andreoli, Maria A., Villa, Luisa L., Longatto-Filho, Adhemar, Baltazar, Fátima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630851/
https://www.ncbi.nlm.nih.gov/pubmed/26525902
http://dx.doi.org/10.1186/s12885-015-1842-4