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EGFR is not a major driver for osteosarcoma cell growth in vitro but contributes to starvation and chemotherapy resistance
BACKGROUND: Enhanced signalling via the epidermal growth factor receptor (EGFR) is a hallmark of multiple human carcinomas. However, in recent years data have accumulated that EGFR might also be hyperactivated in human sarcomas. Aim of this study was to investigate the influence of EGFR inhibition o...
Autores principales: | Sevelda, Florian, Mayr, Lisa, Kubista, Bernd, Lötsch, Daniela, van Schoonhoven, Sushilla, Windhager, Reinhard, Pirker, Christine, Micksche, Michael, Berger, Walter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630894/ https://www.ncbi.nlm.nih.gov/pubmed/26526352 http://dx.doi.org/10.1186/s13046-015-0251-5 |
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