Targeting translocator protein (18 kDa) (TSPO) dampens pro-inflammatory microglia reactivity in the retina and protects from degeneration

BACKGROUND: Reactive microglia are commonly seen in retinal degenerative diseases, and neurotoxic microglia responses can contribute to photoreceptor cell death. We and others have previously shown that translocator protein (18 kDa) (TSPO) is highly induced in retinal degenerations and that the sele...

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Detalles Bibliográficos
Autores principales: Scholz, Rebecca, Caramoy, Albert, Bhuckory, Mohajeet B., Rashid, Khalid, Chen, Mei, Xu, Heping, Grimm, Christian, Langmann, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630900/
https://www.ncbi.nlm.nih.gov/pubmed/26527153
http://dx.doi.org/10.1186/s12974-015-0422-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630900/
https://www.ncbi.nlm.nih.gov/pubmed/26527153
http://dx.doi.org/10.1186/s12974-015-0422-5

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