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Targeting translocator protein (18 kDa) (TSPO) dampens pro-inflammatory microglia reactivity in the retina and protects from degeneration
BACKGROUND: Reactive microglia are commonly seen in retinal degenerative diseases, and neurotoxic microglia responses can contribute to photoreceptor cell death. We and others have previously shown that translocator protein (18 kDa) (TSPO) is highly induced in retinal degenerations and that the sele...
Autores principales: | Scholz, Rebecca, Caramoy, Albert, Bhuckory, Mohajeet B., Rashid, Khalid, Chen, Mei, Xu, Heping, Grimm, Christian, Langmann, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630900/ https://www.ncbi.nlm.nih.gov/pubmed/26527153 http://dx.doi.org/10.1186/s12974-015-0422-5 |
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