Time depended Bcl-2 inhibition might be useful for a targeted drug therapy

BACKGROUND: Over expression of Bcl-2 is frequently observed in several types of cancers and it is one of the prognostic markers in breast cancer. The importance of the Bcl-2 protein as ideal therapeutic target is the dual role of inhibiting apoptosis and autophagy-mediated cell death. Thus, the bcl-...

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Detalles Bibliográficos
Autores principales: Talaiezadeh, Abdolhassan, jalali, Fateme, Galehdari, Hamid, Khodadadi, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630962/
https://www.ncbi.nlm.nih.gov/pubmed/26535028
http://dx.doi.org/10.1186/s12935-015-0254-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630962/
https://www.ncbi.nlm.nih.gov/pubmed/26535028
http://dx.doi.org/10.1186/s12935-015-0254-5

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