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Identification of novel tylosin analogues generated by a wblA disruption mutant of Streptomyces ansochromogenes

BACKGROUND: Streptomyces, as the main source of antibiotics, has been intensively exploited for discovering new drug candidates to combat the evolving pathogens. Disruption of wblA, an actinobacteria-specific gene controlling major developmental transition, can cause the alteration of phenotype and...

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Detalles Bibliográficos
Autores principales: Lu, Cheng, Liao, Guojian, Zhang, Jihui, Tan, Huarong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630966/
https://www.ncbi.nlm.nih.gov/pubmed/26525981
http://dx.doi.org/10.1186/s12934-015-0359-5