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ZIFA: Dimensionality reduction for zero-inflated single-cell gene expression analysis

Single-cell RNA-seq data allows insight into normal cellular function and various disease states through molecular characterization of gene expression on the single cell level. Dimensionality reduction of such high-dimensional data sets is essential for visualization and analysis, but single-cell RN...

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Detalles Bibliográficos
Autores principales: Pierson, Emma, Yau, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630968/
https://www.ncbi.nlm.nih.gov/pubmed/26527291
http://dx.doi.org/10.1186/s13059-015-0805-z