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Simvastatin Suppresses Airway IL-17 and Upregulates IL-10 in Patients With Stable COPD

BACKGROUND: Statins have immunomodulatory properties that may provide beneficial effects in the treatment of COPD. We investigated whether a statin improves the IL-17/IL-10 imbalance in patients with COPD, as has previously been demonstrated in patients with asthma. METHODS: Thirty patients with sta...

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Detalles Bibliográficos
Autores principales: Maneechotesuwan, Kittipong, Wongkajornsilp, Adisak, Adcock, Ian M., Barnes, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American College of Chest Physicians 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631035/
https://www.ncbi.nlm.nih.gov/pubmed/26043025
http://dx.doi.org/10.1378/chest.14-3138