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Overcoming Chemoresistance of Pediatric Ependymoma by Inhibition of STAT3 Signaling

The long-term clinical outcome of pediatric intracranial epepdymoma is poor with a high rate of recurrence. One of the main reasons for this poor outcome is the tumor’s inherent resistance to chemotherapy. Signal transducer and activator of transcription 3 (STAT3) is overactive in many human cancers...

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Detalles Bibliográficos
Autores principales: Phi, Ji Hoon, Choi, Seung-Ah, Kim, Seung-Ki, Wang, Kyu-Chang, Lee, Ji Yeoun, Kim, Dong Gyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631088/
https://www.ncbi.nlm.nih.gov/pubmed/26500028
http://dx.doi.org/10.1016/j.tranon.2015.08.001