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Overcoming Chemoresistance of Pediatric Ependymoma by Inhibition of STAT3 Signaling
The long-term clinical outcome of pediatric intracranial epepdymoma is poor with a high rate of recurrence. One of the main reasons for this poor outcome is the tumor’s inherent resistance to chemotherapy. Signal transducer and activator of transcription 3 (STAT3) is overactive in many human cancers...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Neoplasia Press
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631088/ https://www.ncbi.nlm.nih.gov/pubmed/26500028 http://dx.doi.org/10.1016/j.tranon.2015.08.001 |