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Bacterial calpains and the evolution of the calpain (C2) family of peptidases

Homologues of calpain, often thought to be an essential, cytoplasmic, calcium-dependent cysteine endopeptidase found exclusively in eukaryotes, have been found in bacterial proteomes. The homologues lack calcium-binding sites, have differing domain architectures, and can be secreted or membrane-asso...

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Detalles Bibliográficos
Autor principal: Rawlings, Neil D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631099/
https://www.ncbi.nlm.nih.gov/pubmed/26527411
http://dx.doi.org/10.1186/s13062-015-0095-0