Nordihydroguaiaretic Acid Extends the Lifespan of Drosophila and Mice, Increases Mortality-Related Tumors and Hemorrhagic Diathesis, and Alters Energy Homeostasis in Mice

Mesonordihydroguaiaretic acid (NDGA) extends murine lifespan. The studies reported here describe its dose dependence, effects on body weight, toxicity-related clinical chemistries, and mortality-related pathologies. In flies, we characterized its effects on lifespan, food consumption, body weight, a...

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Detalles Bibliográficos
Autores principales: Spindler, Stephen R., Mote, Patricia L., Lublin, Alex L., Flegal, James M., Dhahbi, Joseph M., Li, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631105/
https://www.ncbi.nlm.nih.gov/pubmed/25380600
http://dx.doi.org/10.1093/gerona/glu190

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631105/
https://www.ncbi.nlm.nih.gov/pubmed/25380600
http://dx.doi.org/10.1093/gerona/glu190

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