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Using Disease-Associated Coding Sequence Variation to Investigate Functional Compensation by Human Paralogous Proteins
Gene duplication enables the functional diversification in species. It is thought that duplicated genes may be able to compensate if the function of one of the gene copies is disrupted. This possibility is extensively debated with some studies reporting proteome-wide compensation, whereas others sug...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Libertas Academica
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631161/ https://www.ncbi.nlm.nih.gov/pubmed/26604664 http://dx.doi.org/10.4137/EBO.S30594 |