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Cell-based Hyper-interleukin 6 or Hyper-interleukin 11 secreting vaccines combined with low dose cyclophosphamide in an orthotopic murine prostate cancer model

BACKGROUND: Cell based vaccines encoding Hyper-IL-6 (H6) and Hyper-IL-11 (H11) present high activity in murine melanoma and renal cancer model. We evaluated the efficacy of cellular vaccines modified with H6 or H11 combined with cyclophosphamide in orthotopic murine prostate cancer model. MATERIAL A...

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Detalles Bibliográficos
Autores principales: Mackiewicz, Jacek, Kotlarski, Marek, Dondajewska, Ewelina, Nowicka-Kotlarska, Anita, Krokowicz, Łukasz, Kazimierczak, Urszula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631279/
https://www.ncbi.nlm.nih.gov/pubmed/26557758
http://dx.doi.org/10.5114/wo.2015.52711