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The role of Snail1 transcription factor in colorectal cancer progression and metastasis

Snail1 is a zinc-finger transcription factor, which plays a role in colorectal cancer development by silencing E-cadherin expression and inducing epithelialmesenchymal transition (EMT). During EMT tumour cells acquire a mesenchymal phenotype that is responsible for their invasive activities. Consequ...

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Detalles Bibliográficos
Autores principales: Brzozowa, Marlena, Michalski, Marek, Wyrobiec, Grzegorz, Piecuch, Adam, Dittfeld, Anna, Harabin-Słowińska, Marzena, Boroń, Dariusz, Wojnicz, Romuald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631295/
https://www.ncbi.nlm.nih.gov/pubmed/26557772
http://dx.doi.org/10.5114/wo.2014.42173