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Analysis of sequence variants in the 3'UTR of CDKN2A gene in melanoma patients

BACKGROUND: The 3'UTR region plays a crucial role in regulating gene expression at posttranscriptional levels. Any changes in sequence in this region can cause numerous pathologies and can also lead to tumour development. The most common changes reported in in the CDKN2A gene are the 148Ala/Thr...

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Detalles Bibliográficos
Autores principales: Przybyła, Anna, Lamperska, Katarzyna, Mackiewicz, Andrzej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631302/
https://www.ncbi.nlm.nih.gov/pubmed/26557774
http://dx.doi.org/10.5114/wo.2015.54227