Salinomycin Promotes Anoikis and Decreases the CD44(+)/CD24(-) Stem-Like Population via Inhibition of STAT3 Activation in MDA-MB-231 Cells

Triple-negative breast cancer (TNBC) is an aggressive tumor subtype with an enriched CD44(+)/CD24(-) stem-like population. Salinomycin is an antibiotic that has been shown to target cancer stem cells (CSC); however, the mechanisms of action involved have not been well characterized. The objective of...

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Detalles Bibliográficos
Autores principales: An, Hyunsook, Kim, Ji Young, Oh, Eunhye, Lee, Nahyun, Cho, Youngkwan, Seo, Jae Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631341/
https://www.ncbi.nlm.nih.gov/pubmed/26528725
http://dx.doi.org/10.1371/journal.pone.0141919

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631341/
https://www.ncbi.nlm.nih.gov/pubmed/26528725
http://dx.doi.org/10.1371/journal.pone.0141919

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