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Salinomycin Promotes Anoikis and Decreases the CD44(+)/CD24(-) Stem-Like Population via Inhibition of STAT3 Activation in MDA-MB-231 Cells
Triple-negative breast cancer (TNBC) is an aggressive tumor subtype with an enriched CD44(+)/CD24(-) stem-like population. Salinomycin is an antibiotic that has been shown to target cancer stem cells (CSC); however, the mechanisms of action involved have not been well characterized. The objective of...
Autores principales: | An, Hyunsook, Kim, Ji Young, Oh, Eunhye, Lee, Nahyun, Cho, Youngkwan, Seo, Jae Hong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631341/ https://www.ncbi.nlm.nih.gov/pubmed/26528725 http://dx.doi.org/10.1371/journal.pone.0141919 |
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