Tumor-targeted and pH-controlled delivery of doxorubicin using gold nanorods for lung cancer therapy

BACKGROUND: In lung cancer, the efficacy of conventional chemotherapy is limited due to poor drug accumulation in tumors and nonspecific cytotoxicity. Resolving these issues will increase therapeutic efficacy. METHODS: GNR-Dox-Tf-NPs (gold nanorod-doxorubicin-transferrin-nanoparticles) were prepared...

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Detalles Bibliográficos
Autores principales: Amreddy, Narsireddy, Muralidharan, Ranganayaki, Babu, Anish, Mehta, Meghna, Johnson, Elyse V, Zhao, Yan D, Munshi, Anupama, Ramesh, Rajagopal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631428/
https://www.ncbi.nlm.nih.gov/pubmed/26604751
http://dx.doi.org/10.2147/IJN.S93237

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631428/
https://www.ncbi.nlm.nih.gov/pubmed/26604751
http://dx.doi.org/10.2147/IJN.S93237

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