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Structure of AadA from Salmonella enterica: a monomeric aminoglycoside (3′′)(9) adenyltransferase

Aminoglycoside resistance is commonly conferred by enzymatic modification of drugs by aminoglycoside-modifying enzymes such as aminoglycoside nucleo­tidyltransferases (ANTs). Here, the first crystal structure of an ANT(3′′)(9) adenyltransferase, AadA from Salmonella enterica, is presented. AadA cata...

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Detalles Bibliográficos
Autores principales: Chen, Yang, Näsvall, Joakim, Wu, Shiying, Andersson, Dan I., Selmer, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631478/
https://www.ncbi.nlm.nih.gov/pubmed/26527143
http://dx.doi.org/10.1107/S1399004715016429