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The structure of the GemC1 coiled coil and its interaction with the Geminin family of coiled-coil proteins

GemC1, together with Idas and Geminin, an important regulator of DNA-replication licensing and differentiation decisions, constitute a superfamily sharing a homologous central coiled-coil domain. To better understand this family of proteins, the crystal structure of a GemC1 coiled-coil domain varian...

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Detalles Bibliográficos
Autores principales: Caillat, Christophe, Fish, Alexander, Pefani, Dafni-Eleftheria, Taraviras, Stavros, Lygerou, Zoi, Perrakis, Anastassis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631479/
https://www.ncbi.nlm.nih.gov/pubmed/26527144
http://dx.doi.org/10.1107/S1399004715016892