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The Influence of LepR Tyrosine Site Mutations on Mouse Ovary Development and Related Gene Expression Changes
Leptin exerts many biological functions, such as in metabolism and reproduction, through binding to and activating the leptin receptor, LepRb, which is expressed in many regions of the brain. To better understand the roles of LepR downstream signaling pathways, Y123F mice, which expressed mutant lep...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631549/ https://www.ncbi.nlm.nih.gov/pubmed/26529315 http://dx.doi.org/10.1371/journal.pone.0141800 |