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The Influence of LepR Tyrosine Site Mutations on Mouse Ovary Development and Related Gene Expression Changes

Leptin exerts many biological functions, such as in metabolism and reproduction, through binding to and activating the leptin receptor, LepRb, which is expressed in many regions of the brain. To better understand the roles of LepR downstream signaling pathways, Y123F mice, which expressed mutant lep...

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Detalles Bibliográficos
Autores principales: Tu, Xiaoyu, Kuang, Zhichao, Gong, Xia, Shi, Yan, Yu, Lin, Shi, Huijuan, Wang, Jian, Sun, Zhaogui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631549/
https://www.ncbi.nlm.nih.gov/pubmed/26529315
http://dx.doi.org/10.1371/journal.pone.0141800