Cargando…

The Influence of LepR Tyrosine Site Mutations on Mouse Ovary Development and Related Gene Expression Changes

Leptin exerts many biological functions, such as in metabolism and reproduction, through binding to and activating the leptin receptor, LepRb, which is expressed in many regions of the brain. To better understand the roles of LepR downstream signaling pathways, Y123F mice, which expressed mutant lep...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tu, Xiaoyu, Kuang, Zhichao, Gong, Xia, Shi, Yan, Yu, Lin, Shi, Huijuan, Wang, Jian, Sun, Zhaogui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631549/ https://www.ncbi.nlm.nih.gov/pubmed/26529315 http://dx.doi.org/10.1371/journal.pone.0141800

Ejemplares similares

Relationship status update for PTP1B and LepR: It׳s complicated()
por: Fischer, Katrin, et al.
Publicado: (2014)

The LepR-mediated leptin transport across brain barriers controls food reward
por: Di Spiezio, Alessandro, et al.
Publicado: (2017)

Associations of MC4R, LEP, and LEPR Polymorphisms with Obesity-Related Parameters in Childhood and Adulthood
por: Raskiliene, Asta, et al.
Publicado: (2021)

Identification of candidate genes for LepR1 resistance against Leptosphaeria maculans in Brassica napus
por: Cantila, Aldrin Y., et al.
Publicado: (2023)

SOCS2 Inhibits Mitochondrial Fatty Acid Oxidation via Suppressing LepR/JAK2/AMPK Signaling Pathway in Mouse Adipocytes
por: Zhang, Tiantian, et al.
Publicado: (2020)

La Lepre
Publicado: (1934)

Association of LEP G2548A and LEPR Q223R Polymorphisms with Cancer Susceptibility: Evidence from a Meta-Analysis
por: He, Jing, et al.
Publicado: (2013)

Co-localisation of the blackleg resistance genes Rlm2 and LepR3 on Brassica napus chromosome A10
por: Larkan, Nicholas J, et al.
Publicado: (2014)

Variations in Adipokine Genes AdipoQ, Lep, and LepR are Associated with Risk for Obesity-Related Metabolic Disease: The Modulatory Role of Gene-Nutrient Interactions
por: Enns, Jennifer Emily, et al.
Publicado: (2011)

The Expression of LEP, LEPR, IGF1 and IL10 in Obesity and the Relationship with microRNAs
por: Viesti A. Collares, Renata, et al.
Publicado: (2014)

The Influence of FTO, FABP2, LEP, LEPR, and MC4R Genes on Obesity Parameters in Physically Active Caucasian Men
por: Maculewicz, Ewelina, et al.
Publicado: (2022)

Polymorphism in LEP and LEPR May Modify Leptin Levels and Represent Risk Factors for Thyroid Cancer
por: Marcello, Marjory Alana, et al.
Publicado: (2015)

Investigation of TCF7L2, LEP and LEPR polymorphisms with esophageal squamous cell carcinomas
por: Qiu, Hao, et al.
Publicado: (2017)

Association of Single Nucleotide Polymorphisms in LEP, LEPR, and PPARG With Humoral Immune Response to Influenza Vaccine
por: Li, Mao, et al.
Publicado: (2021)

Association of PON1, LEP and LEPR Polymorphisms with Susceptibility to Breast Cancer: A Meta-Analysis
por: Sayad, Soheila, et al.
Publicado: (2021)

Restoration of Lepr in β cells of Lepr null mice does not prevent hyperinsulinemia and hyperglycemia
por: D'souza, Anna M., et al.
Publicado: (2017)

Suppression of food intake by Glp1r/Lepr-coexpressing neurons prevents obesity in mouse models
por: Rupp, Alan C., et al.
Publicado: (2023)

Effect modification by region in the associations of LEP G2548A and LEPR Q223R polymorphisms with statin-induced CK elevation
por: Jiang, Shanqun, et al.
Publicado: (2017)

PP2A in LepR+ mesenchymal stem cells contributes to embryonic and postnatal endochondral ossification through Runx2 dephosphorylation
por: Yen, Yu-Ting, et al.
Publicado: (2021)

Identification of novel LEPR mutations in Pakistani families with morbid childhood obesity
por: Niazi, Robina Khan, et al.
Publicado: (2018)

The ovarian estrogen synthesis function was impaired in Y123F mouse and partly restored by exogenous FSH supplement
por: Tu, Xiaoyu, et al.
Publicado: (2018)

Transcriptional Insight Into Brassica napus Resistance Genes LepR3 and Rlm2-Mediated Defense Response Against the Leptosphaeria maculans Infection
por: Zhou, Tengsheng, et al.
Publicado: (2019)

Characterization of a new animal model of metabolic syndrome: the DahlS.Z-Lepr(fa)/Lepr(fa) rat
por: Hattori, T, et al.
Publicado: (2011)

The receptor-like kinase SOBIR1 interacts with Brassica napus LepR3 and is required for Leptosphaeria maculans AvrLm1-triggered immunity
por: Ma, Lisong, et al.
Publicado: (2015)

Altered microRNAs expression profiling in cumulus cells from patients with polycystic ovary syndrome
por: Liu, Suying, et al.
Publicado: (2015)

Winter Hibernation and UCHL1-p34(cdc2) Association in Toad Oocyte Maturation Competence
por: Kuang, Zhichao, et al.
Publicado: (2013)

Investigation of LEP and LEPR polymorphisms with the risk of hepatocellular carcinoma: a case–control study in Eastern Chinese Han population
por: Zhang, Sheng, et al.
Publicado: (2018)

A moderate form of osteogenesis imperfecta caused by compound heterozygous LEPRE1 mutations
por: Santana, Adolfredo, et al.
Publicado: (2018)

LEP (−2548G>A LEP) and LEPR (223Gln>Arg, 109Lys>Arg) polymorphisms as breast cancer risk factors in the Polish female population
por: Hołysz, Hanna, et al.
Publicado: (2021)

PREMATURE CARDIAC SENESCENCE IN DahlS.Z-Lepr(fa)/Lepr(fa) RATS AS A NEW ANIMAL MODEL OF METABOLIC SYNDROME
por: TAKAHASHI, KEIJI, et al.
Publicado: (2014)

Investigation of Associations between Obesity and LEP G2548A and LEPR 668A/G Polymorphisms in a Turkish Population
por: Şahın, Server, et al.
Publicado: (2013)

Xiaoyaosan ameliorates depressive-like behavior and susceptibility to glucose intolerance in rat: involvement of LepR-STAT3/PI3K pathway in hypothalamic arcuate nucleus
por: Qiu, Wenqi, et al.
Publicado: (2023)

Downregulation of SPARC Expression Inhibits the Invasion of Human Trophoblast Cells In Vitro
por: Jiang, Yahong, et al.
Publicado: (2013)

Allelic background of LEPRE1 mutations that cause recessive forms of osteogenesis imperfecta in different populations
por: Pepin, Melanie G, et al.
Publicado: (2013)

Irisin Improves Myocardial Performance and Attenuates Insulin Resistance in Spontaneous Mutation (Lepr(db)) Mice
por: Wang, Jianguo, et al.
Publicado: (2020)

Metformin Suppresses Diethylnitrosamine-Induced Liver Tumorigenesis in Obese and Diabetic C57BL/KsJ-+Lepr(db)/+Lepr(db) Mice
por: Ohno, Tomohiko, et al.
Publicado: (2015)

Changes in beta cell function occur in prediabetes and early disease in the Lepr(db) mouse model of diabetes
por: Do, Oanh H., et al.
Publicado: (2016)

Absence of Functional Leptin Receptor Isoforms in the POUND (Lepr(db/lb)) Mouse Is Associated with Muscle Atrophy and Altered Myoblast Proliferation and Differentiation
por: Arounleut, Phonepasong, et al.
Publicado: (2013)

Association between polymorphisms of LEP, LEPR, DRD2, HTR2A and HTR2C genes and risperidone- or clozapine-induced hyperglycemia
por: Puangpetch, Apichaya, et al.
Publicado: (2019)

Reproductive phase-dependent variation, sexually dimorphic expression and sex steroids-mediated transcriptional regulation of lep and lepr in lymphoid organs of Channa punctata
por: Bakshi, Amrita, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_rhq3f6u7ta241n49pqag7uvdtn