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Animal and human mucosal tissue models to study HIV biomedical interventions: can we predict success?

INTRODUCTION: Preclinical testing plays an integral role in the development of HIV prevention modalities. Several models are used including humanized mice, non-human primates and human mucosal tissue cultures. DISCUSSION: Pharmaceutical development traditionally uses preclinical models to evaluate p...

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Detalles Bibliográficos
Autor principal: Dezzutti, Charlene S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International AIDS Society 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631705/
https://www.ncbi.nlm.nih.gov/pubmed/26530077
http://dx.doi.org/10.7448/IAS.18.1.20301